NCAA1 League Games/Schedule (2021-2022)
| DePaul Games/Schedule | |||||||
| Regular Season | |||||||
| Nov. 9, 2021 | Day 1 | Texas Southern - DePaul | 71-114  | ||||
| Nov. 12, 2021 | Day 4 | Loyola, IL - DePaul | 53-87 | ||||
| Nov. 15, 2021 | Day 7 | DePaul - Texas A | 75-95  | ||||
| Nov. 21, 2021 | Day 13 | Northwestern - DePaul | 75-78 | ||||
| Nov. 25, 2021 | Day 17 | DePaul - Rutgers | 77-74 | ||||
| Nov. 26, 2021 | Day 17 | Arizona (20) - DePaul | 75-68 | ||||
| Nov. 27, 2021 | Day 19 | Vanderbilt - DePaul | 74-91 | ||||
| Dec. 3, 2021 | Day 25 | Butler - DePaul | 64-101 | ||||
| Dec. 5, 2021 | Day 27 | Xavier - DePaul | 85-103 | ||||
| Dec. 9, 2021 | Day 31 | DePaul - Kentucky (16) | 94-85 | ||||
| Dec. 14, 2021 | Day 36 | Nicholls St. - DePaul | 72-100 | ||||
| Dec. 16, 2021 | Day 38 | NIU - DePaul | 71-103 | ||||
| Dec. 19, 2021 | Day 41 | DePaul - St.John's | 107-93 | ||||
| Dec. 22, 2021 | Day 44 | Notre Dame (22) - DePaul | 91-86 | ||||
| Jan. 7, 2022 | Day 57 | DePaul - Providence | 98-77 | ||||
| Jan. 12, 2022 | Day 62 | DePaul - Marquette | 85-88 | ||||
| Jan. 14, 2022 | Day 64 | Villanova - DePaul | 63-75 | ||||
| Jan. 16, 2022 | Day 66 | Georgetown - DePaul | 69-102 | ||||
| Jan. 21, 2022 | Day 71 | DePaul - Butler | 103-69 | ||||
| Jan. 23, 2022 | Day 73 | DePaul - Xavier | 94-74 | ||||
| Jan. 26, 2022 | Day 76 | UConn (6) - DePaul | 80-78 | ||||
| Jan. 28, 2022 | Day 78 | St.John's - DePaul | 88-94 | ||||
| Jan. 30, 2022 | Day 80 | DePaul - Seton Hall | 85-65 | ||||
| Feb. 4, 2022 | Day 85 | Creighton - DePaul | 77-68 | ||||
| Feb. 6, 2022 | Day 87 | Providence - DePaul | 67-88 | ||||
| Feb. 11, 2022 | Day 92 | DePaul - UConn (6) | 60-84 | ||||
| Feb. 13, 2022 | Day 94 | DePaul - Georgetown | 105-104 | ||||
| Feb. 16, 2022 | Day 97 | Marquette - DePaul | 66-77 | ||||
| Feb. 20, 2022 | Day 101 | DePaul - Villanova | 64-73 | ||||
| Feb. 25, 2022 | Day 106 | Seton Hall - DePaul | 94-90 | ||||
| Feb. 27, 2022 | Day 108 | DePaul - Creighton | 90-84 | ||||
| Mar. 5, 2022 | Day 113 | Marquette - DePaul | 105-85 | ||||
| National Tournament Day 1 | |||||||
| Mar. 16, 2022 | Day 122 | DePaul - Dayton | 57-88 | ||||
